Literature reviews

Nobody can read everything.

So how do you find out what is already known about a question, fairly and without picking only the studies you like? That is the job of a literature review.

Companion to Research, simply explained.

Why don't patients finish their antibiotics?
Running example, made up
What a review is

A woven answer, not a pile of summaries.

A weak review lists studies one by one. A good one pulls them together into themes: what keeps coming up, where studies disagree, and what nobody has looked at yet.

A chapter inside your own study A paper of its own (this explainer)
Study A found… Study B found… Study C found… Study D found… Study E found… A B C D E Felt better, so stopped Side effects Cost or forgetting
Studies are made up
Four ways to publish

Same pile of studies, four kinds of review.

They differ in how strict the method is and how focused the question is. Tap each one to see what it asks about our example.

Flexible, broadStrict, focused
The process

Seven steps, one funnel.

Every review moves from a big messy pile to a small set of studies you can trust, and then to one clear story.

Narrative reviews follow these steps loosely. Scoping and systematic reviews follow them strictly and write every step down, so someone else could repeat them.

1 2 3 4 5 6 7 Ask a clear question Choose your words Search the right places Sort the pile Judge quality Pull out the facts Weave it together
Step 1 · Ask a clear question

A vague question finds a vague pile.

"Antibiotics and patients" could mean anything. Break your question into parts with PICO. Tap each letter.

Mapping a topic rather than testing something? Use PCC instead: Population, Concept, Context.

In adults prescribed antibiotics, does a pharmacist reminder call, compared with usual care, help them finish the full course?

Each letter becomes a search concept in Step 2.

Example question
Step 2 · Choose your words

Three little words control the pile.

AND narrows, OR widens, NOT removes. Tap each to see what a database would bring back.

(adherence OR compliance OR "course completion") AND antibiotic*

Use OR between synonyms. A star finds every ending: antibiotic* catches antibiotic and antibiotics.

antibiotic* adherence
Pile size
small, on target
Step 3 · Search the right places

One database is never enough.

Each database covers different journals. Then follow the trail: check what your best papers cite, and who cited them later. This is called snowballing.

PubMedFree. Medicine and health.
ScopusVery broad. Via your library.
CINAHLNursing and allied health.
Cochrane LibraryTrials and reviews.
Google ScholarWide but messy. For checking.
Grey literatureTheses, reports, trial registers.
Older papers it citesNewer papers citing it Your key paper
Step 4 · Sort the pile

From hundreds of hits to a handful that fit.

Decide what counts before you look. Write down who, what and which designs you'll include.
Sort in stages. Titles and abstracts first, then read the survivors in full.
Use two people, working separately, then compare and settle disagreements.
1,240 records found 930 titles & abstracts read 64 read in full 15 included −310 duplicates −866 clearly off-topic −49 wrong patients/design
Numbers are made up
Step 5 · Judge quality

Not every study deserves the same trust.

This is critical appraisal: checking how a study was done, not whether you like its answer. Tap each feature. Would it make you trust the result more, or less?

0 of 6 judged

Step 6 · Pull out the facts

Same questions, asked of every study.

Build a table before you start reading. Fill in the same columns for every included study, so nothing important slips through and studies can be compared side by side.

StudyWhoDesignMain finding
A200 adults, city clinicSurveyMost who stopped said they felt better
B24 adultsInterviewsSide effects made people stop
C310 adults, ruralSurveyCost and forgetting both mattered
D450 adultsTrialReminder call: more finished the course
Studies are made up
Step 7 · Weave it together

This is the part readers actually want.

Synthesis means organising by idea, not by study. Say where studies agree, where they clash, how strong the evidence is, and what's missing.

Example text
Review type 1

Narrative review: an expert's guided tour.

AsksWhat do we know about why patients stop antibiotics early?
HowAn expert reads widely, picks key studies, groups them by theme and gives a view.
Good forIntroducing a topic, textbook chapters, proposing a new idea.
Watch outThe author chooses what goes in, so it can lean towards their own view. Say how you searched.
Check withSANRA, a six-item quality scale for narrative reviews.
Readable and quick, but who picks?
Effort
Review type 2

Scoping review: a map of the evidence.

AsksWhat has been studied on this, in whom, where and how, and what's missing?
HowSearch widely using PCC, then chart the key features of every source into a table or map.
Good forNew or messy topics, and checking whether a systematic review is worth doing.
Watch outIt maps; it doesn't say what works. Quality appraisal is usually optional.
Report withPRISMA-ScR. Register the plan on OSF: PROSPERO doesn't accept scoping reviews.
SurveyInterviewTrial Why stopRemindersCostChildren
Effort Dashed circles = gaps
Map is made up
Review type 3

Systematic review: strict, planned, checkable.

AsksDo pharmacist reminder calls help patients finish their antibiotics?
HowPlan first and register the plan. Search several databases. Two people screen and extract. Appraise every study.
Good forGuiding practice and policy, because anyone can check and repeat it.
Watch outIt takes a team and many months. Narrow, one-database searches don't count.
Report withPRISMA 2020. Register on PROSPERO before data extraction starts.
Plan registered Searched several databases Two people screened Every study appraised Certainty rated (GRADE)
Effort
Review type 4

Meta-analysis: one answer from many numbers.

Used inside a systematic review when studies are similar enough to combine. In this forest plot, each line is a study and bigger boxes carry more weight. The diamond is the combined answer. Tap a study to leave it out.

Trials are made up
Choosing

Which review fits your question?

Answer up to three questions. The right type depends on your question, not on which one sounds most impressive.

Getting published

From finished review to published paper.

1
Plan and register earlySystematic: PROSPERO. Scoping: OSF. Narrative: no registration, but keep notes on how you searched.
2
Follow the checklistPRISMA 2020, PRISMA-ScR or SANRA. Many journals ask you to upload the completed checklist.
3
Choose a genuine journalMatch its scope and readers. Check it with Think. Check. Submit.
4
Answer the reviewersRevise, and reply to every comment point by point.
Common reasons reviews get sent back
Only one database searched Search is years out of date Lists studies, no synthesis No quality appraisal Question too vague No flow diagram
Summary

Six things to remember.

1A review weaves studies together. It doesn't just list them.
2Start with a clear, searchable question, using PICO or PCC.
3Search more than one place, and write down exactly how.
4Decide what counts before you look, then sort the pile in stages.
5Judge each study's quality before you trust its result.
6Pick the review type that fits your question, then follow its checklist.
Keep going

Read widely. Weigh fairly.

New to research?Research, simply explained
→

Written for laypeople and diploma students. The running example, its studies and all its numbers are made up.

Stay in touch